Swine Flu Case in Spain May Point to Global Pandemic

April 30 (Bloomberg) -- A swine-flu patient in Spain who hadn’t traveled to Mexico may signal a new front of the outbreak, potentially heralding the first influenza pandemic in 41 years.

The World Health Organization raised its six-tier alert to 5, the second-highest, and said a pandemic declaration may come soon. It urged countries to make final preparations to deal with a virus that may sweep across the globe.

The WHO has confirmed 154 cases in nine countries, and hundreds of people are being tested for the virus from Australia to New York. Eight of those known to have had swine flu have died, though many more may be carrying the virus and not getting seriously ill, the WHO said. The case in Spain may signal that the disease is being transmitted easily outside of Mexico, where the outbreak began, officials said.

“It is all of humanity that is under threat during a pandemic,” Margaret Chan, WHO director-general, said at a news conference in Geneva yesterday. “The biggest question right now is this: How severe will the pandemic be? All countries should immediately now activate their pandemic plans.”

Batches of seed virus are being developed for potential vaccine production, according to WHO, the UN health agency in Geneva. Paris-based Sanofi-Aventis SA, Baxter International Inc. and GlaxoSmithKline Plc are talking with world health authorities about how to produce a vaccine.

Vaccine Makers ‘Alert’

“Manufacturers are on the alert,” said U.S. Health and Human Services Secretary Kathleen Sebelius. “Once the testing protocol is done and the dosage protocol is done they are ready to begin production, should that be necessary.”

Baxter will receive a sample of the swine flu virus “in the next couple days,” Chris Bona, a spokesman for the Deerfield, Illinois, company, said yesterday.

“We are in constant discussions with the government about how and if we should go ahead,” said Donna Cary, a spokeswoman for Sanofi’s Sanofi-Pasteur unit in Swiftwater, Pennsylvania. London-based Glaxo and Novartis AG of Basel, Switzerland, also are talking with regulators, spokesmen for the companies said.

Today, a Swiss hospital said a patient tested positive for swine flu, the first confirmed case in Switzerland. In Mexico, where the toll is highest, 159 people may have died from the malady, according to government officials, with eight confirmed by laboratory tests.